So if you want to play a different scenario with your friends, I recommend playing this mod. The most popular Civ 6 mod of all time (at the time of writing), despite Civilization 6 firmly overtaking Civ 5 in terms of player numbers, it seems. This sick mod brings these mechanics to Civ V but with the welcome addition of plagues that can spread from city to city.Environment Skin: Sid Meier's Civilization V. Civilization 4 used to have health and disease mechanics for limiting a city's population. The mod offers a healthy challenge for experienced players.